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Pure Encapsulations

SAMe (S-Adenosylmethionine)

SAMe (S-Adenosylmethionine)

Supports methylation, positive mood, glutathione production, cognitive health, liver function, and joint comfort.
  • Size:   
  • Manufacturer:   Pure Encapsulations
  • SKU:   PSAME
  • Stock status:   0
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Pure Encapsulations SAMe (S-Adenosylmethionine) is a single-ingredient capsule delivering 200 mg of SAMe per serving, sourced as S-adenosyl-L-methionine disulfate tosylate and supplied in shelf-stable, acid-resistant vegetarian capsules.

SAMe is a metabolite present in all living cells. It serves as a methyl-group donor and as a precursor molecule relevant to methylation, glutathione production, and polyamine synthesis — roles the manufacturer associates with support for cognitive health, liver function, positive mood, and joint comfort.

Pure Encapsulations formulates this product with hypoallergenic, vegan ingredients and certifies it gluten-free through GFCO. The product is non-GMO, soy-free, and dairy-free, and is free from wheat, eggs, tree nuts, peanuts, artificial colors, flavors and sweeteners, coatings and shellacs, magnesium stearate, trans fats, hydrogenated oils, and unnecessary binders, fillers, and preservatives.

Supplement Facts
Serving size 1 capsule
Servings per container 60
Amount Per Serving%DV
SAMe (S-adenosylmethionine) (from S-adenosyl-L-methionine disulfate tosylate)200 mg*
* Daily value (DV) not established
Other ingredients: vegetarian capsule (cellulose, water), hypoallergenic plant fiber (cellulose), calcium oxide, ascorbyl palmitate, calcium chloride

SAMe (S-adenosylmethionine) — serves as a methyl-group donor in methyltransferase-dependent reactions and as a precursor molecule for glutathione and polyamine synthesis, supporting methylation, positive mood, glutathione production, and joint comfort.

As a dietary supplement, take 1 capsule, 1–2 times daily, between meals, or as directed by a health professional.