What it is: Zinc Lozenge is a lemon-flavored, gluten-free zinc supplementation formula developed by DaVinci Labs, delivering 23 mg of elemental zinc per lozenge in a dual-form combination of Zinc Citrate and Zinc Gluconate — two highly bioavailable organic zinc salts — sweetened with Stevia leaf extract and xylitol for a superior taste profile appropriate for both adults and children. The lozenge delivery format is a clinically relevant distinction from standard capsule or tablet zinc formulas, providing direct mucosal contact with the tissues of the oral cavity and throat during dissolution — an important consideration for immune support protocols targeting upper respiratory health. Designed for practitioner-directed use across a broad range of clinical applications, Zinc Lozenge supports immune function, antioxidant enzyme activity, reproductive health, skin and connective tissue integrity, neurological function, and metabolic regulation through zinc's role as a cofactor for over 200 enzymatic reactions — more than any other mineral in human physiology.
How it works: Zinc Lozenge supports health through zinc's essential and irreplaceable cofactor role across more than 200 enzymatic systems governing virtually every major physiological domain. As a structural and catalytic component of superoxide dismutase (SOD) — the primary cytosolic antioxidant enzyme — zinc supports the neutralization of superoxide free radicals, protecting cells from oxidative damage and contributing to immune cell integrity and longevity. Zinc is a direct regulator of thymulin — a thymic hormone essential for T-lymphocyte maturation and differentiation — and supports the proliferation, activation, and cytokine signaling of natural killer cells, neutrophils, and macrophages, establishing it as a foundational mineral for both innate and adaptive immune competence. The lozenge dissolution format delivers zinc in direct contact with the mucosal epithelia of the oral cavity and throat, supporting the structural integrity and immune barrier function of oropharyngeal tissue with particular clinical relevance during seasonal immune challenges. Zinc supports collagen biosynthesis through its role as a cofactor for procollagen lysyl hydroxylase and other matrix metalloproteinases, contributing to skin integrity, wound healing, bone matrix formation, and joint connective tissue health. In reproductive health, zinc is uniquely concentrated in prostate tissue and seminal plasma, where it supports testosterone synthesis, spermatogenesis, sperm motility, and 5-alpha reductase regulation — making zinc status a critical determinant of male reproductive function. Zinc additionally supports insulin receptor signaling, carbohydrate metabolism, amino acid synthesis, brain development, and heavy metal detoxification through its role in metallothionein — a zinc-dependent protein that binds and sequesters cadmium, lead, and mercury in hepatic and renal tissue.
When to use it: Zinc Lozenge is appropriate for practitioner-directed use in adult and pediatric clients requiring broad-spectrum zinc repletion or targeted support across immune, reproductive, dermatological, musculoskeletal, neurological, and metabolic health domains. It is particularly well-suited for clients presenting with known or suspected zinc insufficiency — a clinically prevalent finding given that dietary zinc deficiency affects an estimated 90% of the population according to orthomolecular nutrition research — as well as for those with elevated zinc requirements including smokers, oral contraceptive users, pregnant or planning-to-conceive clients, and individuals with skin blemish concerns or joint discomfort. The AM/PM dosing schedule of one lozenge morning and evening supports consistent zinc availability throughout the day. The lozenge should be allowed to dissolve fully in the mouth to maximize both mucosal tissue contact and systemic absorption.
Serving Size: 1 Lozenge
Servings Per Container: 60
Suggested Use: As a dietary supplement, take 1 lozenge in the AM and 1 lozenge in the PM, or as directed by your healthcare practitioner. Allow lozenge to dissolve fully in mouth.
| Amount Per Serving | % Daily Value | |
| Calories | 5 | — |
| Total Carbohydrates | 1 g | 0%† |
| Zinc (as Zinc Citrate & Zinc Gluconate) | 23 mg | 209% |
| Stevia Leaf Extract | 4 mg | * |
† Percent Daily Values are based on a 2,000-calorie diet.
* Daily Value not established. Percent Daily Values are based on a 2,000-calorie diet.
Other Ingredients: Xylitol, stearic acid, vegetable stearate, citric acid, honey powder, silica, natural lemon flavor.
Caution: If pregnant or nursing, consult your healthcare practitioner before taking this product. Keep out of reach of children. Store in a cool, dry place. Color may vary due to natural ingredient variation.
✓ Gluten Free
Key Ingredients
Zinc (as Zinc Citrate & Zinc Gluconate) — 23 mg This dual-form zinc complex combines two of the most bioavailable and gastrointestinally well-tolerated organic zinc salts — zinc citrate and zinc gluconate — delivering 209% of the daily value of elemental zinc per lozenge in a form that maximizes intestinal absorption and systemic utilization compared to inorganic zinc salts such as zinc oxide or zinc sulfate. Zinc is an essential trace mineral that functions as a structural or catalytic cofactor for over 200 enzymes — more than any other mineral in human physiology — governing processes spanning superoxide dismutase-mediated antioxidant defense, T-lymphocyte and natural killer cell maturation, collagen and proteoglycan biosynthesis, testosterone and spermatogenesis support, insulin receptor signaling, metallothionein-mediated heavy metal detoxification, and brain-derived neurotrophic factor (BDNF) activity in neuronal tissue. The lozenge delivery format provides direct mucosal contact of zinc with the oral cavity and oropharyngeal tissue during dissolution, supporting the structural and immune barrier integrity of throat mucosa through a localized zinc-mediated mechanism that complements the systemic benefits of absorbed zinc — making this format particularly clinically relevant for upper respiratory and throat health support protocols.
