What it is:
ADK 10™ is a targeted, three-nutrient fat-soluble vitamin formula developed by DaVinci Labs, delivering clinically meaningful doses of Vitamin A (as retinyl palmitate), Vitamin D3 (as cholecalciferol) at 10,000 IU, and Vitamin K2 (as Menaquinone-7) in a single vegetarian capsule. These three fat-soluble vitamins function as an interdependent triad with well-established synergistic activity across bone metabolism, cardiovascular health, calcium regulation, and immune function. Designed for practitioner-directed use, ADK 10™ is formulated for clients requiring high-potency vitamin D3 support alongside the complementary cofactors necessary to direct calcium utilization appropriately and protect vascular tissue from calcification.
How it works:
ADK 10™ operates through tightly integrated fat-soluble vitamin pathways that collectively govern calcium metabolism, bone remodeling, and cardiovascular protection. Vitamin D3 (as cholecalciferol), the most bioavailable and physiologically active dietary form of vitamin D, binds to the nuclear vitamin D receptor (VDR) to upregulate intestinal calcium and phosphorus absorption, promote renal calcium reabsorption, and support osteoblast differentiation — processes essential to healthy bone mineral density and immune regulation. Vitamin K2 (as Menaquinone-7/MK-7), the long-chain, most bioavailable form of vitamin K2, activates two critical calcium-regulating proteins: osteocalcin, which binds calcium into bone matrix, and matrix Gla-protein (MGP), which actively inhibits arterial and soft tissue calcification. This dual carboxylation activity ensures that the increased calcium mobilized by Vitamin D3 is directed into bone rather than deposited in vascular or soft tissue, providing critical cardiovascular protection alongside skeletal support. Vitamin A (as retinyl palmitate) complements this axis by supporting osteoclast and osteoblast activity in bone remodeling, regulating VDR expression to modulate vitamin D activity, and supporting mucosal and immune barrier integrity. Together, these three nutrients form a coordinated fat-soluble vitamin system that supports bone structure, density, healthy remodeling, appropriate calcium utilization, and cardiovascular function.
When to use it:
ADK 10™ is appropriate for practitioner-directed use in adult clients requiring high-potency vitamin D3 repletion alongside synergistic cofactor support for calcium metabolism and cardiovascular protection. It is particularly well-suited for protocols addressing vitamin D insufficiency or deficiency, osteopenia, osteoporosis risk, immune support, and calcium dysregulation, as well as for clients with limited sun exposure, malabsorption concerns, or elevated inflammatory burden. Due to the 10,000 IU vitamin D3 dose, practitioner oversight and periodic serum 25(OH)D monitoring are recommended throughout the protocol. This formula is contraindicated in pregnancy and nursing, and in clients with blood-clotting disorders or those taking anticoagulant or antiplatelet medications without appropriate clinical supervision.
Serving Size: 1 Capsule
Servings Per Container: 90
Suggested Use: As a dietary supplement, take 1 capsule daily, or as directed by your healthcare practitioner.
| Amount Per Serving | % Daily Value | |
|
Vitamin A (as Retinyl Palmitate) |
1,500 mcg | 167% |
|
Vitamin D3 (as Cholecalciferol) |
250 mcg (10,000 IU) | 1,250% |
|
Vitamin K2 (as Menaquinone-7) |
500 mcg | † |
† Daily Value not established.
Other Ingredients: Microcrystalline cellulose, hypromellose (capsule), vegetarian leucine.
Caution: Do not take if pregnant, nursing, or planning to become pregnant. If you have any pre-existing conditions or are taking any medications, consult your healthcare practitioner before use. If you have a blood-clotting disorder or are taking anticoagulant/antiplatelet drugs such as Coumadin (Warfarin), do not take this product without consulting your healthcare practitioner. Individuals taking more than 50 mcg (2,000 IU) of Vitamin D per day should have their vitamin D levels monitored. This product is not intended for long-term use and should be used under the supervision of your healthcare practitioner. Keep out of reach of children. Store in a cool, dry place. Color may vary due to natural ingredient variation.
✓ Vegetarian ✓ Gluten Free ✓ Soy Free ✓ Non-GMO
Key Ingredients
Vitamin D3 (as Cholecalciferol) — 250 mcg (10,000 IU) Cholecalciferol is the preferred, most physiologically active dietary form of vitamin D, identical to the form synthesized endogenously in human skin upon UVB exposure, and substantially more effective at raising and sustaining serum 25(OH)D concentrations than the plant-derived ergocalciferol (D2) form. Following hepatic and renal hydroxylation to its active hormone form 1,25-dihydroxyvitamin D3 (calcitriol), it binds to the nuclear vitamin D receptor (VDR) to regulate over 200 gene targets involved in intestinal calcium and phosphorus absorption, osteoblast differentiation, renal calcium reabsorption, and innate and adaptive immune regulation. At 10,000 IU per serving, this formula delivers a high-potency clinical dose appropriate for supervised repletion protocols in clients with confirmed vitamin D insufficiency, immune compromise, or elevated bone loss risk.
Vitamin K2 (as Menaquinone-7) — 500 mcg Menaquinone-7 (MK-7) is the long-chain, most bioavailable and longest-acting form of vitamin K2, with a serum half-life significantly exceeding that of shorter-chain menaquinones and vitamin K1, enabling sustained carboxylation activity throughout peripheral tissues including bone and vasculature. MK-7 activates osteocalcin — the bone matrix protein responsible for binding calcium into hydroxyapatite — and matrix Gla-protein (MGP), the primary inhibitor of vascular and soft tissue calcification, ensuring that calcium mobilized by vitamin D3 activity is appropriately directed into skeletal tissue rather than arterial walls. This dual osteocalcin and MGP carboxylation activity makes MK-7 an indispensable cofactor in high-dose vitamin D3 protocols, providing complementary bone-building and cardiovascular protection within a single formula.
Vitamin A (as Retinyl Palmitate) — 1,500 mcg Retinyl palmitate is a preformed, esterified vitamin A compound — the primary storage form of vitamin A in the body — offering direct bioavailability without the conversion limitations associated with provitamin A carotenoids such as beta-carotene, which varies substantially based on individual genetic and digestive factors. Vitamin A plays an essential regulatory role in bone remodeling by modulating both osteoblast and osteoclast activity, and directly influences vitamin D receptor (VDR) expression through its interaction with retinoid X receptors (RXR), which heterodimerize with VDR to govern the transcriptional activity of vitamin D. The inclusion of retinyl palmitate at 1,500 mcg ensures appropriate vitamin A status to support mucosal and epithelial barrier integrity, healthy immune function, and the balanced vitamin A-to-D ratio necessary to prevent competitive antagonism between these two fat-soluble nutrient systems.
