Nattokinase Plus (60)

What It Is

Nattokinase Plus is a professional-grade fibrinolytic enzyme formula delivering three synergistic active compounds in a single vegetarian capsule: Nattokinase NSP-2 at 150 mg with a verified activity of 20,000 fibrin units (FU) per gram, Serratiopeptidase at 150 mg with an activity of 120,000 units per gram, and Rutin at 200 mg, a bioflavonoid with well-established antioxidant and vascular-supportive properties. The nattokinase in this formula is derived from Natto, a traditional Japanese fermented soy food, and is free of Vitamin K, making it appropriate for clients where vitamin K intake requires monitoring. The formula is encapsulated in a vegetable cellulose capsule and is free of gluten and GMO ingredients.

How It Works

Nattokinase is a serine protease enzyme with direct fibrinolytic activity, meaning it acts enzymatically on fibrin, the insoluble protein network that forms the structural basis of blood clots. By promoting the breakdown of fibrin and supporting the body's natural fibrinolytic processes, nattokinase contributes to healthy blood viscosity, normal circulation and the maintenance of vascular patency. Its activity at 20,000 FU per gram reflects a high potency standardization, ensuring consistent and clinically meaningful enzyme activity per dose. Serratiopeptidase, derived from the beneficial bacteria Serratia marcescens, is a complementary fibrinolytic and proteolytic enzyme with particular affinity for breaking down non-living protein debris including mucus, fibrin deposits and arterial plaque precursors. Its inclusion alongside nattokinase creates a broader spectrum of enzymatic fibrinolytic activity than either enzyme alone. Rutin, a bioflavonoid glycoside found naturally in buckwheat, citrus and certain botanicals, contributes to the formula by acting as a potent scavenger of superoxide radicals and supporting the structural integrity of capillary walls. Rutin is also understood to support healthy platelet aggregation, which complements the vascular support provided by both fibrinolytic enzymes. Together these three ingredients address blood flow and vascular health through distinct but synergistic mechanisms.

When to Use It

Nattokinase Plus is suited for practitioners working with clients presenting with suboptimal circulation, a history of sluggish fibrinolytic activity, or cardiovascular risk profiles that include concerns around blood viscosity and vascular inflammation. It is particularly appropriate as a non-pharmaceutical adjunct for clients who are not candidates for or who prefer to avoid conventional anticoagulant therapy, though practitioners should exercise careful clinical judgment and client screening given the formula's fibrinolytic activity. The between-meal dosing protocol is clinically important, as systemic enzyme activity is maximized when the formula is taken in a fasted state, away from food-related proteolytic demand. Practitioners should also note the formula's soy derivation and exercise appropriate judgment for clients with soy sensitivities, though the nattokinase itself is a highly purified enzyme isolate with negligible residual soy protein content.