What it is: Hair Effects™ is a comprehensive, vegetarian multi-ingredient hair health formula developed by DaVinci Labs, delivering fourteen clinically relevant ingredients across three therapeutic categories — DHT and 5-alpha reductase modulation, structural hair and scalp support, and antioxidant and follicle protection — within a single three-capsule daily serving. The formula combines Saw Palmetto berry extract (standardized to 45% fatty acids), Beta-Sitosterol Complex, DIM® (proprietary bioavailability-enhanced diindolylmethane), GLA Powder, Pygeum africanum bark extract, and Stinging Nettle root extract to address the hormonal and enzymatic drivers of hair loss; MSM, L-Cysteine, DL-Methionine, and Horsetail Rush extract to provide the sulfur substrate and structural amino acid building blocks for keratin, collagen, and hair fiber synthesis; and Biotin, Zinc Picolinate, Copper Sulfate, Grape Seed Extract, and Green Tea extract to support follicle vitality, pigmentation, scalp microcirculation, and antioxidant protection. Designed for practitioner-directed use in both male and female hair health protocols, Hair Effects™ addresses hair loss through multiple root causes simultaneously — making it appropriate as a standalone comprehensive hair support formula for clients of either sex.
How it works: Hair Effects™ supports hair health through three coordinated and complementary mechanisms targeting hormonal balance, structural biosynthesis, and scalp and follicle vascular and antioxidant support. Dihydrotestosterone (DHT) — the potent androgen formed from testosterone by 5-alpha reductase — is the primary hormonal driver of androgenic alopecia in both men and women. Saw Palmetto berry extract (360 mg, yielding 162 mg free fatty acids), Beta-Sitosterol Complex (75 mg, 40% beta-sitosterol), and DIM® (50 mg) each inhibit 5-alpha reductase through complementary fatty acid, phytosterol, and indole mechanisms — collectively reducing intrafollicular DHT accumulation and its follicle-miniaturizing effect. GLA Powder (50 mg) provides gamma-linolenic acid, an omega-6 fatty acid with additional 5-alpha reductase inhibitory activity. Pygeum africanum bark extract (75 mg, yielding 1.87 mg plant sterols) and Stinging Nettle root extract (50 mg) provide complementary follicle structural integrity support and aromatase modulation, addressing the estrogen conversion arm of the androgenic hormone imbalance. On the structural biosynthesis side, MSM (200 mg) provides bioavailable organic sulfur as the primary substrate for keratin synthesis — the structural protein of hair fibers — with adequate sulfur supply directly supporting stronger, more resilient hair that breaks less easily. L-Cysteine (200 mg) and DL-Methionine (500 mg), the two sulfur-containing amino acids, provide the specific amino acid building blocks for keratin and collagen synthesis in both hair fiber and scalp tissue. Biotin (600 mcg, 2,000% DV) serves as the essential coenzyme for carboxylase enzymes involved in fatty acid synthesis required for sebaceous gland function and hair follicle metabolism. Zinc Picolinate (15 mg) and Copper Sulfate (3 mg) support hair follicle cell division, melanin synthesis for pigmentation maintenance, and follicle structural integrity. Grape Seed Extract (200 mg, yielding 190 mg proanthocyanidins) supports scalp microcirculation and follicle protection through its capillary-strengthening proanthocyanidin content. Horsetail Rush (Equisetum arvense) extract provides naturally occurring silica to support hair shaft structural integrity and tensile strength.
When to use it: Hair Effects™ is appropriate for practitioner-directed use in adult male and female clients experiencing hair loss, thinning, reduced hair texture, premature graying, or scalp health concerns with a hormonal, nutritional, or structural component. It is particularly well-suited for integration into protocols addressing androgenic alopecia, hormonal hair loss in perimenopausal women, nutritional deficiency-related hair changes, and comprehensive hair and skin health programs. Three capsules daily with food — which may be divided between AM and PM — supports sustained delivery of both the hormonal-modulating botanical ingredients and the structural amino acid and cofactor components. This formula is contraindicated in pregnancy, nursing, and for clients planning to become pregnant.
Serving Size: 3 Capsules
Servings Per Container: 30
Suggested Use: As a dietary supplement, take 3 capsules daily with food. The daily amount may be divided between AM and PM, or as directed by your healthcare practitioner.
| Amount Per Serving | % Daily Value | |
| Biotin | 600 mcg | 2,000% |
| Zinc (as Zinc Picolinate) | 15 mg | 136% |
| Copper (as Copper Sulfate) | 3 mg | 333% |
| DL-Methionine | 500 mg | * |
| Saw Palmetto (Serenoa repens) Berry Extract (yielding Fatty Acids 162 mg) | 360 mg | * |
| Methylsulfonylmethane (MSM) | 200 mg | * |
| L-Cysteine | 200 mg | * |
| Grape Seed Extract (yielding Proanthocyanidins 190 mg) | 200 mg | * |
| Horsetail Rush (Equisetum arvense) Herb Extract | 100 mg | * |
| Pygeum africanum Bark Extract (yielding Plant Sterols 1.87 mg) | 75 mg | * |
| Plant Sterol Complex (40% Beta-Sitosterol) | 75 mg | * |
| Gamma-Linolenic Acid (GLA) Powder (50%) | 50 mg | * |
| Stinging Nettle (Urtica dioica) Root Extract | 50 mg | * |
| DIM® (a proprietary enhanced bioavailability complex of starch, diindolylmethane, Vitamin E as tocophersolan, phosphatidylcholine, silica) | 50 mg | * |
| Green Tea Extract (yielding EGCG 15 mg) | 50 mg | * |
* Daily Value not established. Percent Daily Values are based on a 2,000-calorie diet.
Other Ingredients: Hypromellose (capsule), microcrystalline cellulose, vegetarian leucine.
Caution: If pregnant, nursing, or planning to become pregnant, do not take this product. Keep out of reach of children. Store in a cool, dry place. Color may vary due to natural ingredient variation.
✓ Gluten Free ✓ Vegetarian ✓ Non-GMO
Key Ingredients
Saw Palmetto (Serenoa repens) Berry Extract — 360 mg (yielding 162 mg Fatty Acids) Saw Palmetto berry extract, standardized to 45% free fatty acids, delivers the primary bioactive lipophilic fraction responsible for its well-characterized 5-alpha reductase inhibitory and anti-androgenic activity in follicular tissue. The free fatty acid content — particularly lauric, oleic, and myristic acids — competitively inhibits both type I and type II isoforms of 5-alpha reductase, reducing the intrafollicular conversion of testosterone to the more potent dihydrotestosterone (DHT) that drives progressive follicle miniaturization and androgenic alopecia in both male and female pattern hair loss. At 360 mg per serving yielding 162 mg of standardized fatty acids, this formula delivers a meaningful clinical dose of the DHT-reducing botanical most extensively studied for hair loss support, forming the hormonal cornerstone of this formula's multi-mechanism anti-androgenic approach.
MSM (Methylsulfonylmethane) — 200 mg MSM is a naturally occurring organosulfur compound and one of the most bioavailable dietary forms of elemental sulfur — the third most abundant mineral in the human body and an irreplaceable structural component of keratin, the fibrous protein constituting approximately 95% of hair fiber composition. Adequate organic sulfur availability from MSM directly supports the cross-linking of cysteine disulfide bonds within the keratin polypeptide chains that confer tensile strength, elasticity, and structural integrity to individual hair fibers — with sulfur deficiency associated with weaker, more brittle hair with increased breakage tendency. MSM additionally supports scalp health by promoting blood flow to the dermal papilla — the vascular structure at the base of each hair follicle responsible for delivering oxygen and nutrients to actively dividing follicle matrix cells — and contributes sulfur substrate to collagen synthesis in the scalp dermis that provides the structural scaffolding for follicle anchorage.
L-Cysteine — 200 mg & DL-Methionine — 500 mg L-Cysteine and DL-Methionine are the two sulfur-containing amino acids that serve as the direct structural building blocks for keratin biosynthesis and the primary determinants of hair fiber quality and strength. L-Cysteine provides the cysteine residues that form the disulfide bonds responsible for the mechanical strength and cross-linking density of the keratin matrix — with higher cysteine content producing stronger, more resilient hair fibers — while simultaneously serving as the rate-limiting precursor for glutathione synthesis in scalp and follicle tissue, protecting actively dividing follicle cells from oxidative damage. DL-Methionine — the sulfur-containing essential amino acid — is transsulfurated to cysteine in the methionine cycle, providing the primary metabolic source of cysteine for keratin synthesis when dietary cysteine is insufficient, while additionally supporting collagen biosynthesis in the scalp dermis through its role as the methyl group donor for S-adenosylmethionine (SAMe) in collagen methylation reactions. Together, these two sulfur amino acids provide the full structural amino acid complement for keratin and collagen synthesis in hair fiber, follicle, and scalp tissue.
Grape Seed Extract — 200 mg (yielding 190 mg Proanthocyanidins) Grape seed extract standardized to 95% oligomeric proanthocyanidins (OPCs) supports hair follicle health through two primary mechanisms: capillary-strengthening activity in scalp microvasculature and direct growth factor-mediated follicle stimulation. Proanthocyanidins support the structural integrity of capillary endothelium in the scalp dermal microcirculation by cross-linking collagen fibers within capillary walls and inhibiting hyaluronidase — the enzyme that degrades the connective tissue matrix surrounding follicle blood vessels — ensuring optimal blood flow, oxygen, and nutrient delivery to the dermal papilla of each hair follicle. Research has additionally demonstrated that proanthocyanidins from grape seed promote the transition of hair follicles from the telogen (resting) to anagen (active growth) phase through upregulation of vascular endothelial growth factor (VEGF) and β-catenin signaling in follicle dermal papilla cells — providing a growth factor-mediated mechanism that directly supports active hair follicle proliferation.
