What it is: Adipo-Leptin Benefits™ is a vegetarian, four-ingredient weight management hormone and metabolism support formula developed by DaVinci Labs, combining Green Coffee Bean Extract, Brown Seaweed (Laminaria japonica) whole plant extract, WellTrim® iG (IGOB131®) African Mango (Irvingia gabonensis) seed extract, and GreenSelect® Green Tea (Camellia sinensis) Leaf Extract/Phosphatidylcholine Phytosome Complex. WellTrim® iG is a trademark of Icon Group LLC, and IGOB131® is a trademark of Gateway Health Alliances, Inc., protected under U.S. Patent 7,537,790. GreenSelect® and Phytosome™ are registered trademarks of Indena S.p.A., Italy. This formula is specifically designed to address the adipokine hormone axis — targeting Leptin and Adiponectin, two fat tissue-derived hormones that govern energy expenditure, appetite, fat cell behavior, glucose regulation, and inflammatory balance — making it particularly appropriate for clients who have reached a weight management plateau or who present with hormonal metabolic resistance. Designed for practitioner-directed use in weight management and cardiometabolic protocols, including as a complement to GLP-1-based programs.
How it works: Adipo-Leptin Benefits™ supports weight management through four complementary and synergistic mechanisms targeting adipokine hormone balance, GLP-1 support, thermogenesis, glucose regulation, and fat oxidation. WellTrim® iG African Mango (Irvingia gabonensis) seed extract — the most clinically studied ingredient for Leptin and Adiponectin modulation — supports healthy levels of these metabolic adipokines, promoting appetite satiety through Leptin signaling and healthy fat cell behavior and glucose-insulin balance through Adiponectin activity, while simultaneously helping to inhibit adipogenesis and promote a favorable shift in body composition. Brown Seaweed (Laminaria japonica) provides fucoxanthin — a marine carotenoid stored preferentially in adipose tissue — that functions as a thermogenic antioxidant, supporting healthy metabolic rate through uncoupling protein-1 (UCP1) upregulation in fat tissue, and additionally stimulates GLP-1 secretion from intestinal L-cells to support appetite regulation and efficient glucose metabolism. Green Coffee Bean Extract contributes chlorogenic acids that slow postprandial glucose release from the intestine and moderate hepatic glucose production, supporting blood sugar levels already within normal ranges and reducing carbohydrate cravings associated with postprandial glucose spikes, alongside caffeic acid content that provides a gentle, naturally low-caffeine energy boost to support exercise motivation. GreenSelect® Green Tea Phytosome — a patented Indena S.p.A. phytosome complex of Camellia sinensisleaf extract and phosphatidylcholine delivering dramatically enhanced EGCG bioavailability — independently stimulates GLP-1 production and supports healthy body composition through fat oxidation promotion, while its highly bioavailable catechin content provides complementary metabolic and antioxidant activity validated in multiple published human clinical trials. Together, these four ingredients address weight management from the hormonal (adipokine), appetite (GLP-1), thermogenic (fucoxanthin), and glucose-regulatory (chlorogenic acid) dimensions simultaneously.
When to use it: Adipo-Leptin Benefits™ is appropriate for practitioner-directed use in adult clients requiring hormonal and metabolic support for weight management — particularly those who have reached a plateau on existing weight management programs, clients with Leptin resistance or suboptimal Adiponectin activity contributing to metabolic resistance, those seeking to support GLP-1-mediated appetite regulation alongside or independent of pharmaceutical GLP-1 agents, and clients with cardiometabolic risk factors where healthy blood sugar, insulin balance, and body composition are simultaneous clinical objectives. Two capsules daily with appropriate dietary support provides the formula's full four-ingredient metabolic hormone and GLP-1 support matrix.
Serving Size: 2 Capsules
Servings Per Container: 30
Suggested Use: As a dietary supplement, take 2 capsules daily, or as directed by your healthcare practitioner.
|
Ingredient |
Amount Per Serving |
% Daily Value |
|
Green Coffee Bean Extract |
300 mg |
* |
|
Brown Seaweed (Laminaria japonica) Whole Plant Extract |
200 mg |
* |
|
WellTrim® iG (IGOB131®) African Mango (Irvingia gabonensis) Seed Extract |
150 mg |
* |
|
GreenSelect® Green Tea (Camellia sinensis Leaf Extract / Phosphatidylcholine Complex) |
150 mg |
* |
* Daily Value not established.
Other Ingredients: Hypromellose (capsule), microcrystalline cellulose, vegetarian leucine.
Caution: If pregnant or nursing, consult your healthcare practitioner before taking this product. Keep out of reach of children. Store in a cool, dry place. Color may vary due to natural ingredient variation.
✓ Gluten Free ✓ Vegetarian ✓ Soy Free
Key Ingredients
WellTrim® iG (IGOB131®) African Mango (Irvingia gabonensis) Seed Extract — 150 mg WellTrim® iG is a patented, proprietary Irvingia gabonensis seed extract (IGOB131®, U.S. Patent 7,537,790) — the most clinically validated and standardized form of African Mango seed extract available — specifically selected for its documented activity on the adipokine hormones Leptin and Adiponectin that govern energy balance, appetite regulation, and fat cell metabolism. African Mango seed extract supports Leptin sensitivity by reducing serum C-reactive protein levels that interfere with Leptin receptor signaling, and promotes favorable Adiponectin activity — the anti-inflammatory, insulin-sensitizing adipokine that declines with increasing adiposity — supporting healthy fat cell behavior, glucose-insulin balance, and a favorable shift toward fat oxidation over fat storage. At 150 mg per serving, WellTrim® iG provides the clinically studied dose format that has demonstrated favorable outcomes for body weight, waist circumference, and metabolic hormone levels in peer-reviewed human clinical trials, establishing it as the hormonal and metabolic cornerstone of this formula.
GreenSelect® Green Tea Phytosome — 150 mg GreenSelect® is a patented green tea catechin/phosphatidylcholine phytosome complex developed by Indena S.p.A. (Italy) using their Phytosome More Bioavailable® technology, which molecularly binds EGCG and other catechins to phosphatidylcholine to create a lipid-compatible structure that dramatically enhances gastrointestinal absorption and systemic bioavailability — with human pharmacokinetic data demonstrating substantially greater plasma catechin concentrations compared to unformulated green tea extract at equivalent doses. GreenSelect® independently supports GLP-1 secretion from intestinal L-cells, promotes healthy body composition through fat oxidation enhancement and adipogenesis inhibition, and provides cardiovascular antioxidant protection through its highly bioavailable EGCG content. Multiple published human clinical trials with GreenSelect® specifically — not generic green tea — have demonstrated significant improvements in body weight, fat mass, and waist circumference, validating the phytosome formulation's clinical superiority for metabolic applications.
Brown Seaweed (Laminaria japonica) Whole Plant Extract — 200 mg Brown Seaweed (Laminaria japonica) whole plant extract provides fucoxanthin — a xanthophyll marine carotenoid with a unique metabolic mechanism that distinguishes it from terrestrial carotenoids — alongside fucoidan and alginate polysaccharides that provide complementary GLP-1 stimulation and prebiotic gut health activity. Fucoxanthin is selectively stored in adipose tissue where it upregulates uncoupling protein-1 (UCP1) in white adipose tissue — a thermogenic protein typically expressed only in brown adipose tissue — effectively converting white fat's energy-storage function toward heat-generating thermogenic activity and supporting increased metabolic rate without central nervous system stimulation. Additionally, fucoxanthin and the polysaccharide content of Laminaria japonica stimulate intestinal L-cell GLP-1 secretion, supporting the appetite-regulatory and glucose-metabolic hormonal axis that complements the formula's Leptin and Adiponectin activity for comprehensive hormonal weight management support.
Green Coffee Bean Extract — 300 mg Green Coffee Bean Extract delivers a concentrated chlorogenic acid complex from unroasted Coffea beans — preserving the high phenolic acid content substantially reduced by roasting — with chlorogenic acids functioning as selective inhibitors of intestinal alpha-glucosidase and hepatic glucose-6-phosphatase activity that slow both postprandial glucose absorption from the intestine and hepatic glucose output, supporting blood sugar levels already within the normal range and attenuating the glucose spike-and-crash cycle that drives carbohydrate cravings and appetite dysregulation. Chlorogenic acids additionally support a favorable shift in the lipid-to-carbohydrate oxidation ratio — promoting preferential fat oxidation relative to carbohydrate burning during metabolic activity — while caffeic acid content provides a gentle, naturally low-caffeine energy boost that supports exercise motivation and physical activity engagement without the adverse cardiovascular effects of high-caffeine stimulants.
