{"product_id":"davinci-vitamin-k2-resveratrol-60","title":"Vitamin K2 + Resveratrol (60 Capsules)","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat it is:\u003c\/strong\u003e Vitamin K2 + Resveratrol is a targeted, two-ingredient bone, cardiovascular, and neurological support formula developed by DaVinci Labs, combining 500 mcg of Vitamin K2 (as Menaquinone-7\/MK-7) with 100 mg of Japanese Knotweed (\u003cem\u003ePolygonum cuspidatum\u003c\/em\u003e) root extract standardized to yield 50 mg of trans-resveratrol per capsule. This novel dual-ingredient combination is designed to address bone mineral density, vascular health, and free radical protection through complementary and synergistic mechanisms — with Vitamin K2 providing carboxylation-dependent calcium direction into bone matrix and arterial calcification inhibition, and trans-Resveratrol providing phytoestrogen-mediated bone mineralization support, polyphenol antioxidant cardiovascular protection, and sirtuin pathway-mediated cellular health activity. Designed for practitioner-directed use, Vitamin K2 + Resveratrol is particularly well-suited for women's bone health protocols during and after menopause, and for comprehensive cardiovascular antioxidant support programs.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eHow it works:\u003c\/strong\u003e Vitamin K2 + Resveratrol supports bone, cardiovascular, and neurological health through two distinct and complementary mechanisms that converge on calcium metabolism, vascular protection, and antioxidant defense. Vitamin K2 (as Menaquinone-7\/MK-7) functions as the essential enzyme cofactor for gamma-carboxylase, which carboxylates two critical calcium-regulating proteins: osteocalcin, which requires carboxylation to develop the glutamate-derived structural binding domains necessary for calcium anchoring within hydroxyapatite bone matrix; and matrix Gla-protein (MGP), the most potent physiological inhibitor of arterial and soft tissue calcification, which requires K2-dependent carboxylation to actively redirect calcium away from vascular walls. Additionally, Vitamin K2 exerts regulatory influence over Vitamins A and D with respect to osteoclast and osteoblast activity, contributing to the hormonal coordination of bone remodeling. Trans-Resveratrol (50 mg per capsule from \u003cem\u003ePolygonum cuspidatum\u003c\/em\u003e root) — the biologically active isomer of resveratrol — supports bone health through its established phytoestrogen activity, binding to estrogen receptors (particularly ERβ) in osteoblasts to promote bone formation and mineralization processes, a mechanism of particular clinical relevance for women experiencing declining estrogen levels during and after menopause where estrogen-dependent bone loss accelerates. Resveratrol's polyphenolic antioxidant activity supports cardiovascular health through inhibition of LDL oxidation, reduction of platelet aggregation tendency, support of blood vessel pliability and flexibility, and activation of SIRT1 — the NAD-dependent deacetylase enzyme linked to cardiovascular protection, mitochondrial biogenesis, and neuronal health through its role in cellular stress response and inflammation modulation.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhen to use it:\u003c\/strong\u003e Vitamin K2 + Resveratrol is appropriate for practitioner-directed use in adult clients requiring targeted bone mineral density support, vascular calcification protection, and cardiovascular antioxidant defense — with particular clinical relevance for perimenopausal and postmenopausal women where both estrogen-mediated bone loss and cardiovascular risk are elevated. It is well-suited for integration into bone health protocols as a companion to Vitamin D3 supplementation (providing the K2 cofactor essential for safe and effective high-dose D3 supplementation), into women's health and menopause support programs leveraging resveratrol's phytoestrogen bone-mineralization activity, and into cardiovascular antioxidant protocols where LDL oxidation protection and vascular pliability support are clinical objectives. One capsule daily with food supports consistent MK-7 carboxylation activity and trans-resveratrol bioavailability.\u003c\/p\u003e","brand":"Davinci Labs","offers":[{"title":"Default Title","offer_id":46856856010978,"sku":"DL-VitaminK2Resveratrol","price":17.56,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0071\/8707\/1066\/files\/020015J.060-_F.jpg?v=1776870122","url":"https:\/\/mhpvitamins.com\/products\/davinci-vitamin-k2-resveratrol-60","provider":"Mountain States Health Products Inc","version":"1.0","type":"link"}