{"product_id":"davinci-hepaticlear-60","title":"HepaticClear™ (60 Capsules)","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat it is:\u003c\/strong\u003e HepaticClear™ is a comprehensive, vegetarian eleven-ingredient hepatic detoxification and liver support formula developed by DaVinci Labs, delivering targeted nutritional cofactors across all six Phase II detoxification conjugation pathways alongside Phase I cytochrome P450 membrane support, antioxidant protection, and glutathione biosynthesis support. The formula features Milk Thistle (\u003cem\u003eSilybum marianum\u003c\/em\u003e) seed extract (standardized to 160 mg silymarin), N-Acetyl Cysteine, L-Methionine, L-Glycine, Alpha Lipoic Acid, Calcium D-Glucarate, DIM® (proprietary bioavailability-enhanced diindolylmethane), Choline, Inositol, Turmeric root powder, and Biotin — each selected for its specific and documented role in hepatic Phase I or Phase II detoxification biochemistry. Designed for practitioner-directed use in liver health, detoxification, hormonal clearance, and hepatoprotective protocols, HepaticClear™ provides a mechanistically comprehensive approach to supporting the full arc of hepatic toxin processing — from initial cytochrome P450 transformation through final conjugation and excretion.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eHow it works:\u003c\/strong\u003e HepaticClear™ supports hepatic detoxification through precisely targeted nutritional support across both phases of liver detoxification. Phase I detoxification — mediated by the cytochrome P450 (CYP450) enzyme family embedded in hepatocyte cell membranes — requires healthy membrane integrity as its structural foundation: Choline (80 mg, as choline bitartrate) and Inositol (25 mg) are essential phospholipid membrane components that maintain the structural integrity of hepatocyte cell membranes in which the CYP450 enzymes are anchored, while simultaneously supporting hepatic fat and cholesterol metabolism. Biotin (50 mcg) supports cell growth, fat metabolism, and cellular energy generation within the liver. DIM® (25 mg, proprietary bioavailability-enhanced diindolylmethane complex) supports both Phase I and Phase II detoxification activity and specifically promotes the detoxification and clearance of estrogen metabolites through CYP1A1\/1A2 modulation. Phase II detoxification — involving six conjugation pathways that neutralize Phase I-transformed intermediates for urinary or biliary excretion — is addressed across all six pathways: Calcium D-Glucarate supports glucuronidation by providing glucuronic acid substrate and inhibiting beta-glucuronidase to ensure elimination of fungal toxins, steroid hormones, and environmental xenobiotics; L-Glycine (25 mg) supports amino acid conjugation — the pathway that combines glycine with and neutralizes various toxins for biliary excretion, particularly important in clients on low-protein diets with chronic toxin exposure; L-Methionine (100 mg) provides the methionine substrate for SAMe production and methylation — one of the most critical Phase II pathways governing hormonal and neurotransmitter detoxification — while contributing sulfur for glutathione and sulfation pathway support; N-Acetyl Cysteine (50 mg) directly replenishes glutathione as the rate-limiting cysteine precursor for the glutathione conjugation pathway — the liver's primary detoxification route for reactive electrophilic intermediates; and Alpha Lipoic Acid (20 mg) provides dual-soluble antioxidant support to recycle glutathione, vitamin C, and vitamin E from their oxidized forms, amplifying the antioxidant network protecting hepatocytes from oxidative damage generated during Phase I metabolism. Milk Thistle extract (200 mg, yielding 160 mg silymarin) provides hepatocellular membrane stabilization, direct silymarin-mediated antioxidant protection, and silybin-driven glutathione synthesis support and hepatocyte regeneration promotion. Turmeric root powder contributes curcuminoid antioxidants that protect liver cells from free radical damage and support gallbladder function for bile storage and release.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhen to use it:\u003c\/strong\u003e HepaticClear™ is appropriate for practitioner-directed use in adult clients requiring comprehensive Phase I and Phase II hepatic detoxification support, hepatocellular protection, and liver health maintenance. It is particularly well-suited for integration into detoxification protocols, post-pharmaceutical or post-antibiotic liver recovery programs, hormonal clearance and estrogen metabolism support protocols, environmental toxic burden programs, mold exposure recovery, and foundational liver wellness support for clients with elevated hepatic oxidative stress or suboptimal Phase II conjugation capacity. Two capsules daily — one taken twice daily — provides sustained hepatic detoxification cofactor support throughout the day. This formula is contraindicated in pregnancy, nursing, and for clients planning to become pregnant.\u003c\/p\u003e","brand":"Davinci Labs","offers":[{"title":"Default Title","offer_id":46856853684450,"sku":"DL-Hepaticlear60","price":18.36,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0071\/8707\/1066\/files\/0200423.060-_F.jpg?v=1777046414","url":"https:\/\/mhpvitamins.com\/products\/davinci-hepaticlear-60","provider":"Mountain States Health Products Inc","version":"1.0","type":"link"}