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    Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. It is similar to cyanocobalamin without the cyanide moiety. Adenosylcobalamin is an activated form similar to methylcobalamin. While methylcobalamin is found in the cytosol of cells and predominates in blood and other fluids, adenosylcobalamin is the major form of vitamin B12 stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism for the enzyme methylmalonyl-CoA mutase used to produce succinyl-CoA. Optimal levels also support healthy synthesis of neuronal myelin.* Unique blend of adenosylcobalamin and hydroxycobalamin offers unmethylated B12 to promote nerve and mitochondrial health.* Learn More

  2. B-COMPLEX (with Metafolin & Instrinsic Factor)

    B-COMPLEX (with Metafolin & Instrinsic Factor)

    Douglas Laboratories® B-Complex is unique, including Metafolin®, Methylcobalamin Vitamin B12, and Intrinsic Factor in its formulation. Metafolin® contains only the S isomer of 5_MTHF and has been shown to be the only form of folate to be able to cross the blood_brain barrier. Studies indicate that methylcobalamin, a coenzyme form of B12, may be better utilized and better retained in the body. Intrinsic factor is a protein produced by cells in the stomach lining and is needed for the intestines to absorb vitamin B12 efficiently. Learn More

  3. B12 Liquid 1,000 mcg

    B12 Liquid 1,000 mcg

    B12 liquid supports nerve cell health, neurological function, energy production and immune system health. Learn More

  4. B12 Liquid 5000 mcg

    B12 Liquid 5000 mcg

    B12 liquid supports nerve cell health, neurological function, energy production and immune system health. Learn More

  5. L-Methyl Folate

    L-Methyl Folate

    Highly bioavailable folate as Metafolin, 1,700 mcg Folate deficiencies are common as many individuals do not consume enough folate-rich foods and dietary folates are readily destroyed by cooking or processing. Although typically included in multivitamins, some individuals do not effectively methylate and convert folic acid, the form of folate commonly found in fortified foods and supplements, into its active form thus are still at risk of deficiency. Metafolin® L-5-MTHF, an active, methylated form of folate, requires no additional metabolic steps to be used by the body, thus it is often the preferred choice for those with absorption or metabolic defects. L-MethylFolate efficiently supports methylation, DNA biosynthesis, homocysteine metabolism, and nervous system function. Supplies 1,700 mcg per capsule. Learn More

  6. Methyl B12 Intraoral Liposomal **NEW LOWER PRICING**

    Methyl B12 Intraoral Liposomal **NEW LOWER PRICING**

    Vitamin B12 is an essential water-soluble nutrient for the normal function of several body systems, including the cardiovascular, nervous, and digestive systems. It also helps support liver function and the detoxification process. A diet without adequate B12 can adversely affect the production of basic building blocks, like RNA and DNA, but also the production of red blood cells. Research shows that many people can have difficulties metabolizing and absorbing B-12, especially when digestive and/or intestinal functioning is suboptimal. For these people, intravenous therapy or intraoral liposomal delivery are the best methods for achieving rapid shifts in blood levels of this key nutrient. Learn More

  7. Methyl B12 Plus (90)

    Methyl B12 Plus (90)

    Methyl B12 Plus provides Metafolin® L-methylfolate and vitamin B12 methylcobalamin in a great-tasting tablet that dissolves in the mouth. Methylfolate and methylcobalamin are the predominant forms of B vitamins commonly found in cells that do not require additional conversion in the body. Methyl B12 Plus dissolvable tablets are sweetened naturally with Xylitol and flavored with natural black cherry and vanilla. Learn More



    Methyl Factors provides vitamins B6, B12, and folate in a unique liquid form to support the reduction of homocysteine levels for heart health. Learn More



    Methyl Folate provides 1,000 mcg of Metafolin®, a patented form of (6S) 5-methyltetrahydrofolate (5-MTHF). 5-MTHF is the naturally occurring, predominant form of folate commonly found in cells and is essential for overall health, as it participates as a cofactor in a reaction that involves the remethylation of homocysteine to methionine. Metafolin® is directly usable by the body and has been shown to be the only form of folate to cross the blood-brain barrier. Learn More



    Helps Support the Cardiovasular System* Learn More

  11. MethylAssist


    Provides activated B vitamins to support healthy methylation, cardiovascular, neural and emotional health. Learn More

  12. Methylcobalamin


    Methylcobalamin offers advanced support for a healthy nervous system. Learn More



    Active form of vitamin B12. Learn More

    Out of stock

  14. MTHFR Niacin

    MTHFR Niacin

    Key benefits and actions

    • Involved in carbohydrate, fat, and protein metabolism
    • Essential for the release of energy from food
    • May help maintain healthy circulation
    • May help stabilize methylation in cases of over-supplementation
    Learn More

    Out of stock

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